Innovative Animal Products offers a comprehensive line of veterinary orthopedic supplies and devices related to External Fracture Fixation, Internal Fracture Fixation, and Joint Stabilization.
IRAP II |
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Arthrex IRAP™ II System Defects in articular cartilage can induce osteoarthritis by causing molecular changes in the synovial fluid. Research in molecular biology discovered the major inducer of steoarthritis was the general inflammatory cytokine interleukin-1 (IL-1) which plays a key role in accelerating tissue destruction and the repair mechanisms. In a healthy joint, IL-1 and interleukin-1 receptor antagonist (IL-1Ra) are in balanced concentrations. In cases of osteoarthritis, there is not sufficient IL-1Ra produced to block the destructive effects of the increased IL-1. The result is inflammation, joint pain, and eventually cartilage destruction. In the Arthrex IRAP II, monocytes (a type of white blood cell) bind to the glass beads. The cells are then stimulated to produce regenerative and anti-inflammatory proteins without the addition of drugs. This process takes place over an incubation period of 24 hours.
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The IRAP II serum has high concentrations of regenerative and inhibitory proteins that block the effects of destructive proteins like IL-1, by filling the receptors on the cartilage with IL-1Ra. 
